Even in these special and tough days, we are about to launch. We sincerely thank Cell Stem Cell for this great opportunity to briefly introduce our forthcoming lab to the community. The original text is as follows:
Cell Fate and Embryogenesis
Fan Zhou
Tsinghua University
My forthcoming lab focuses on understanding how multi-dimensional molecular architecture (e.g., gene networks coordinated with epigenetic factors) regulate cell fate decisions and transitions during mammalian/human embryogenesis. We aim to integrate single-cell in vitro/vivo functional identification, single-cell omics analysis, and genetic manipulation to link the genome with cumulative cellular phenotypes. Our work mainly includes the following: (1) employing/developing single-cell multi-omics analysis to uncover the molecular patterns of lineage specialization during embryonic development; (2) establishing in vitro/vivo models to understand the regulatory mechanism of cell fate transition during embryogenesis from the phenotypic/functional dimension; and (3) exploring the regulatory principles in embryo implantation and tumor evolution in reproductive system.
With years of training in stem cell and early embryo development, I am excited to have the opportunity to independently carry out research on cell fate and embryogenesis at Tsinghua. Understanding the principles of cell fate will not only shed light on how orderly embryo body plans emerge from a single-cell fertilized egg to build a complex and highly functional organism, but also reveal how potential regulators trigger diseases such as cancer, essentially a disordered transformation of cell fates. I am looking forward to this unfolding journey with all of my future lab members.
Welcome to apply and join us (zhoufanlove@126.com)! We sincerely read all the e-mails.
Fan Zhou's Blog Site 
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